Sfoglia per Autore "Kourtzelis, I."
Items 1-6 di 6
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Endothelin-1 Signaling Promotes Fibrosis In Vitro in a Bronchopulmonary Dysplasia Model by Activating the Extrinsic Coagulation Cascade
Kambas, K.; Chrysanthopoulou, A.; Kourtzelis, I.; Skordala, M.; Mitroulis, I.; Rafail, S.; Vradelis, S.; Sigalas, I.; Wu, Y. Q.; Speletas, M.; Kolios, G.; Ritis, K. (2011)Neonatal respiratory distress syndrome can progress to bronchopulmonary dysplasia (BPD), a serious pulmonary fibrotic disorder. Given the involvement of the extrinsic coagulation cascade in animal models of lung fibrosis, ... -
Fast and reliable mutation detection of the complete exon 11-15 JAK2 coding region using non-isotopic RNase cleavage assay (NIRCA)
Kambas, K.; Mitroulis, I.; Kourtzelis, I.; Chrysanthopoulou, A.; Speletas, M.; Ritis, K. (2009)The screening for JAK2 V617F mutation in patients with polycythemia vera, essential thrombocythemia, and idiopathic myelofibrosis offers crucial information for the final diagnosis of these disorders. Recently, several ... -
Genetic analysis of C5a receptors in neutrophils from patients with familial Mediterranean fever
Apostolidou, E.; Kambas, K.; Chrysanthopoulou, A.; Kourtzelis, I.; Speletas, M.; Ritis, K.; Mitroulis, I. (2012)Familial Mediterranean fever (FMF) is an autoinflammatory disease, characterized by MEFV gene mutations and self-limited recurrent episodes of fever and localized serositis. Complement system is a key regulator of the ... -
In vivo induction of the autophagic machinery in human bone marrow cells during Leishmania donovani complex infection
Mitroulis, I.; Kourtzelis, I.; Papadopoulos, V. P.; Mimidis, K.; Speletas, M.; Ritis, K. (2009)Autophagy is a homeostatic process promoting cell survival in periods of stress. The induction of the autophagic machinery has also been implicated in both innate and adaptive immunity. Leishmania donovani, which is the ... -
Leptin induces the expression of functional tissue factor in human neutrophils and peripheral blood mononuclear cells through JAK2-dependent mechanisms and TNF alpha involvement
Rafail, S.; Ritis, K.; Schaefer, K.; Kourtzelis, I.; Speletas, M.; Doumas, M.; Giaglis, S.; Kambas, K.; Konstantinides, S.; Kartalis, G. (2008)Introduction: Leptin is an adipocyte-derived cytokine primarily involved in the regulation of body weight and energy balance. In vivo studies suggest that leptin promotes platelet aggregation and thrombosis. Neutrophils ... -
Regulation of the autophagic machinery in human neutrophils
Mitroulis, I.; Kourtzelis, I.; Kambas, K.; Rafail, S.; Chrysanthopoulou, A.; Speletas, M.; Ritis, K. (2010)The induction of the autophagy machinery, a process for the catabolism of cytosolic proteins and organelles, constitutes a crucial mechanism in innate immunity. However, the involvement of autophagy in human neutrophils ...